LITTLE KNOWN FACTS ABOUT MAKATUSSIN SYROP.

desvenlafaxine will increase the level or impact of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Watch. Desvenlafaxine inhibits CYP2D6; with increased desvenlafaxine doses (ie, four hundred mg) minimize the CYP2D6 substrate dose by as much as 50%; no dosage adjustment required with desvenlafaxine doses 7 consecutive days promp